Check out our new results on Nano Letters! We have observed coherent hybridization of magnons and phonons first ever in monolayer antiferromagnet FePSe3 by cavity-enhanced magneto-Raman spectroscopy. The coupling remains robust even in zero magnetic field down to 2D limit in a single atomic layer. We also discovered theoretically that such magnon-phonon hybridization enables nontrivial band inversion between longitudinal and transverse optical phonons and guarantee magnetic-field-controlled topological phase transition. The 2D topological magnon–phonon hybridization would potentially offer a new route toward quantum phononics and magnonics with an ultrasmall footprint.